EXPRESSION OF CYP1A IN THE HEPATOPANCREAS OF MERLUCCIUS

MERLUCCIUS, TRIGLA LUCERNA, AND LIZA RAMADA (PISCES) IN THE

WIDER VICINITY OF BAR HARBOR MONTENEGRO

 

MIRJANA MIHAILOVIĆ1, JELENA ARAMBAŠIĆ1, DESANKA BOGOJEVIĆ1, SVETLANA DINIĆ1, NEVENA GRDOVIĆ1,

ILIJANA GRIGOROV1, SVETLANA IVANOVIĆ-MATIĆ1, SVETLANA LABUS-BLAGOJEVIĆ2, VESNA MARTINOVIĆ1,

M. PETROVIĆ1, ALEKSANDRA USKOKOVIĆ1, MELITA VIDAKOVIĆ1, and G. POZNANOVIĆ1

 

1 Laboratory of Molecular Biology, Siniša Stanković Institute for Biological Research, 11060 Belgrade, Serbia;

2 Milan Jovanović-Batut Institute for Public Health, 11000 Belgrade, Serbia

 

Abstract – The expression of CYP1A, a biomarker for the presence of xenobiotic compounds, was examined in three fish species from the wider vicinity of Bar harbor in winter and spring. Induction of CYP1A was observed in winter and increased further in spring. Several PCBs were found in seawater in winter. They decreased below the limit of detection in spring, when the PAH fluorene was detected. It is concluded that the constant presence of CYP1A expression is probably due to pollutants in the environment, whereas increased expression of CYP1A in spring results from exposure of the fish to fluorene.